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  • German and British Teams Begin Trials for Covid-19 Vaccine

    As COVID-19 continues to cause relentless infections and death worldwide, the race to develop an effective vaccine against the virus has gathered pace in recent days. In Oxford, England, a clinical trial of an experimental vaccine will begin for the first time on humans • Full Story

    Vos Iz Neias

    As COVID-19 continues to cause relentless infections and death worldwide, the race to develop an effective vaccine against the virus has gathered pace in recent days. In Oxford, England, a clinical trial of an experimental vaccine will begin for the first time on humans.

    The trial is the result of a collaboration between the university’s Jenner Institute and the Oxford Vaccine Group clinical teams. Work began on developing the vaccine in early January.

    Meanwhile on Wednesday, German regulatory body PEI approved the country’s first trials on human volunteers for a vaccine developed by German firm Biontech and US giant Pfizer.

    Though there are now around 150 development projects worldwide, the German and British plans are among only five clinical trials on humans which have been approved across the globe.

    The Oxford trial will involve 510 volunteers aged between 18 and 55 in the first phase.

    Research director Professor Sarah Gilbert estimated that it has around an 80 percent chance of being successful.The institute aims to develop a million doses of the vaccine by September, so as to distribute it as quickly as possible after approval.

    The Oxford trial is part of a nationwide effort in the UK which since Friday has been spearheaded by a government taskforce.

    In Germany, meanwhile, the PEI said its approval of the Biontech trial marked a “significant step” in making a vaccine available as soon as possible.

    In the first phase, it will see “200 healthy volunteers aged between 18 and 55 years” vaccinated with variants of the vaccine, while the second phase could see the inclusion of volunteers who belonged to high-risk groups.

    On Wednesday, Biontech CEO Ugur Sahin told a press conference that tests would begin at the end of April. He added that the firm expected to have collected first data by the end of June or beginning of July.

    Biontech also said that they and Pfizer hoped to gain regulatory approval soon to test the same vaccine candidate in the US.

    The PEI meanwhile claimed that further clinical trials of COVID-19 vaccine candidates will start in Germany in the next few months.

    There are currently no approved vaccines or medication for the COVID-19 disease and experts estimate that it will take at least 12 to 18 months to develop a new vaccine. Medical officials are concerned that COVID-19 may return again before the new vaccine is readily available and may develop more mutations which are resistant to vaccines being produced at present.

    Last week, UN Secretary-General Antonio Guterres said a vaccine was the only thing that would return “normalcy” to the world, and called for development projects to be accelerated.

    A UN resolution adopted on Monday, meanwhile, called for “equitable, efficient and timely” access to any vaccine that might be developed.

    Aside from Biontech and Oxford, three other clinical trials on humans have been approved worldwide since mid-March, with Chinese and US developers among the first to move.

    Beijing approved the first trial for a vaccine developed by the military-backed Academy of Military Medical Sciences and Hong Kong-listed biotech firm CanSino Bio on March 16.

    That day the US drug developer Moderna said it had begun human tests for their vaccine with the US National Institutes of Health.

    Another US lab, San Diego-based Inovio Pharmaceuticals, began first phase human trials on April 6.

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